Akkermansia muciniphila AH39-Shanghai Unibio Lab Co., Ltd.

Scientific Probiotics, Make Health Easier

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Akkernize® AKK AH39
The Gold Standard in Metabolic

The first Chinese-isolated Akkermansia strain to complete international human RCT clinical trials. Clinically proven to reduce waist circumference, suppress appetite, and strengthen the gut barrier.

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Akkernize® AKK AH39

Akkernize® AKK AH39

Beyond basic digestion, true wellness is metabolic resilience. Pasteurized Akkernize® AKK AH39 (our Akkermansia muciniphila) is a next-generation probiotic clinically shown to transform your gut environment.

Restoring the Gut Barrier

Akkernize® AKK AH39 enhances tight junction expression and boosts regulatory T-cells (Tregs), thereby rebuilding your gut barrier.

Improving Metabolic Markers

Akkernize® AKK AH39 significantly reduces waist circumference, body fat, and appetite scores in just 8 weeks.

Why Akkernize® AKK AH39?

Not all Akkermansia strains are equal. AH39 is a proprietary, comprehensively researched strain isolated from healthy human donors.

99.8% Protein Similarity 99.8% Protein Similarity hover
99.8% Protein Similarity
Highly consistent with the model strain BAA-835.
FDA sGRAS Certified FDA sGRAS Certified hover
FDA sGRAS Certified
Self-affirmed safety for global markets.
50% Market Share 50% Market Share hover
50% Market Share
The world's leading AKK raw material by volume and research.
VPro® Technology VPro® Technology hover
VPro® Technology
5-layer micro-encapsulation for maximum stability.

Proven in Human Trials
8 Weeks to a Better You

Based on the 2025 Randomized Double-Blind Clinical Trial (Aalipanah et al., *Clinical Nutrition ESPEN*).

  • Metabolic Reset: Significant reduction in Waist Circumference and Body Fat Percentage. Metabolic Reset: Significant reduction in Waist Circumference and Body Fat Percentage.

    Metabolic Reset: Significant reduction in Waist Circumference and Body Fat Percentage.

  • Appetite Control: Notable decrease in appetite scores vs. placebo. Appetite Control: Notable decrease in appetite scores vs. placebo.

    Appetite Control: Notable decrease in appetite scores vs. placebo.

  • Liver Support: Improved AST (Aspartate Aminotransferase) levels. Liver Support: Improved AST (Aspartate Aminotransferase) levels.

    Liver Support: Improved AST (Aspartate Aminotransferase) levels.

  • Gut Health: Replenishes the mucus lining and reduces systemic inflammation. Gut Health: Replenishes the mucus lining and reduces systemic inflammation.

    Gut Health: Replenishes the mucus lining and reduces systemic inflammation.

The Mechanism (How it Works)

Dual-Action Pathway

  • GLP-1 Activation

    GLP-1 Activation

    1.The P9 protein secreted by AH39 stimulates L-cells to release GLP-1, naturally regulating blood sugar and satiety.
  • Barrier Reinforcement

    Barrier Reinforcement

    2.The heat-resistant Amuc_1100 protein activates TLR-2, tightening the gut junction and preventing "Leaky Gut".

Built on Science, Driven by Innovation

2010

🔬Studies revealed that Akkermansia muciniphila is inversely associated with obesity, diabetes and metabolic syndrome, with higher abundance observed in healthy individuals.

2017

🔬FAHBZ39, 26-year-old female, from Bozhou, Anhui. GDMCC No: 65707

2021

🔬A milestone in industrialization; the EU authorized its pasteurized form as a Novel Food.

2023

🔬Launch of the world’s first commercial AKK ingredient – AKK AH39.

2024

🔬Canada approved AKK under its Natural Health Product (NHP) framework.

2025

🔬 Awarded FDA sGRAS certification.
China's first strain to complete an international human RCT clinical trial.

From Research to Reality

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