Clostridium butyricum CCFM1299-Shanghai Unibio Lab Co., Ltd.

A New Generation of Functional Microbiome Strain

Clostridium butyricum CCFM1299 is a proprietary butyrate-producing probiotic strain developed through advanced microbiome and metabolic research.

Unlike conventional probiotics primarily focused on digestive balance, CCFM1299 has been investigated for its role in:

Host metabolic regulation
Energy expenditure
Bile acid metabolism
Gut microbiota modulation
Thermogenesis-related pathways

Scientific Highlights

Butyrate-Producing Capability

Naturally produces butyrate to support microbiome and intestinal ecosystem function.
Energy Metabolism Regulation

Investigated for promoting energy expenditure and thermogenesis-related activity.
Bile Acid Modulation

Associated with modulation of host bile acid metabolism and related metabolic pathways.
Microbiome-Host Interaction

Supports next-generation microbiome-targeted product development.
Immune & Metabolic Crosstalk

Research explored immune-related signaling and adipose tissue regulation.

Research Overview

CCFM1299 is supported by proprietary strain research, patent development, and published scientific investigation related to microbiome modulation and metabolic health.

Research Areas

Obesity and metabolic regulation

Thermogenesis-related pathways

Gut microbiota modulation

Bile acid metabolism

Host-microbiome interaction

Published in Nutrients (2023)

Clostridium butyricum Strain CCFM1299 Reduces Obesity via Increasing Energy Expenditure and Modulating Host Bile Acid Metabolism
Supported by proprietary patent research

A Clostridium butyricum Strain for Alleviating Obesity and lts Applications

Key Findings from Preclinical Evaluation

Reduced Body Weight Gain

CCFM1299 intervention demonstrated significant reduction in body weight gain under high-fat diet conditions.

Increased Energy Expenditure

Higher oxygen consumption and CO₂ production were observed during intervention.

Thermogenesis-Related Gene Activation

Enhanced expression of Ucp1, Pparγ, Pgc1α and Prdm16 was observed in BAT.

Metabolic Biomarker Modulation

Associated with changes in bile acid metabolites including UDCA and THDCA.

Clostridium butyricum CCFM1299-Shanghai Unibio Lab Co., Ltd.

Home

Next-Gen Probiotics

Science

Solutions

About Us

News

Contact Us